Dynamic Force Spectroscopy and Biomolecular Recognition download pdf
Dynamic Force Spectroscopy and Biomolecular Recognition download pdf
Dynamic Force Spectroscopy and Biomolecular Recognition.cSalvatore Cannistraro
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Author: Salvatore Cannistraro
Number of Pages: 270 pages
Published Date: 27 Jan 2012
Publisher: Taylor & Francis Inc
Publication Country: Bosa Roca, United States
Language: English
ISBN: 9781439862377
Download Link: Dynamic Force Spectroscopy and Biomolecular Recognition
---------------------------------------------------------------
Molecular recognition, also known as biorecognition, is the heart of all biological interactions. Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies and is finding wider applications in areas such as biophysics and polymer science. In six chapters, Dynamic Force Spectroscopy and Biomolecular Recognition covers the most recent ideas and advances in the field of DFS applied to biorecognition: *Chapter 1: Reviews the basic and novel aspects of biorecognition and discusses the emerging capabilities of single-molecule techniques to disclose kinetic properties and molecular mechanisms usually hidden in bulk measurements *Chapter 2: Describes the basic principle of atomic force microsocopy (AFM) and DFS, with particular attention to instrumental and theoretical aspects more strictly related to the study of biomolecules *Chapter 3: Overviews the theoretical background in which experimental data taken in nonequilibrum measurements of biomolecular unbinding forces are extrapolated to equilibrium conditions *Chapter 4: Reviews the most common and efficient strategies adopted in DFS experiments to immobilize the interacting biomolecules to the AFM tip and to the substrate *Chapter 5: Presents and discusses the most representative aspects related to the analysis of DFS data and the challenges of integrating well-defined criteria to calibrate data in automatic routinary procedures *Chapter 6: Overviews the most relevant DFS applications to study biorecognition processes, including the biotin/avidin pair, and selected results on various biological complexes, including antigen/antibody, proteins/DNA, and complexes involved in adhesion processes *Chapter 7: Summarizes the main results obtained by DFS applied to study biorecognition processes with forthcoming theoretical and experimental advances Although DFS is a widespread, worldwide technique, no books focused on this subject have been available until now. Dynamic Force Spectroscopy and Biomolecular Recognition provides the state of the art of experimental data analysis and theoretical procedures, making it a useful tool for researchers applying DFS to study biorecognition processes.
Read online Dynamic Force Spectroscopy and Biomolecular Recognition Buy Dynamic Force Spectroscopy and Biomolecular Recognition Download Dynamic Force Spectroscopy and Biomolecular Recognition for pc, mac, kindle, readers Download to iPad/iPhone/iOS, B&N nook Dynamic Force Spectroscopy and Biomolecular Recognition
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Dynamic Force Spectroscopy and Biomolecular Recognition.cSalvatore Cannistraro
Author: Salvatore Cannistraro
Number of Pages: 270 pages
Published Date: 27 Jan 2012
Publisher: Taylor & Francis Inc
Publication Country: Bosa Roca, United States
Language: English
ISBN: 9781439862377
Download Link: Dynamic Force Spectroscopy and Biomolecular Recognition
---------------------------------------------------------------
Molecular recognition, also known as biorecognition, is the heart of all biological interactions. Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies and is finding wider applications in areas such as biophysics and polymer science. In six chapters, Dynamic Force Spectroscopy and Biomolecular Recognition covers the most recent ideas and advances in the field of DFS applied to biorecognition: *Chapter 1: Reviews the basic and novel aspects of biorecognition and discusses the emerging capabilities of single-molecule techniques to disclose kinetic properties and molecular mechanisms usually hidden in bulk measurements *Chapter 2: Describes the basic principle of atomic force microsocopy (AFM) and DFS, with particular attention to instrumental and theoretical aspects more strictly related to the study of biomolecules *Chapter 3: Overviews the theoretical background in which experimental data taken in nonequilibrum measurements of biomolecular unbinding forces are extrapolated to equilibrium conditions *Chapter 4: Reviews the most common and efficient strategies adopted in DFS experiments to immobilize the interacting biomolecules to the AFM tip and to the substrate *Chapter 5: Presents and discusses the most representative aspects related to the analysis of DFS data and the challenges of integrating well-defined criteria to calibrate data in automatic routinary procedures *Chapter 6: Overviews the most relevant DFS applications to study biorecognition processes, including the biotin/avidin pair, and selected results on various biological complexes, including antigen/antibody, proteins/DNA, and complexes involved in adhesion processes *Chapter 7: Summarizes the main results obtained by DFS applied to study biorecognition processes with forthcoming theoretical and experimental advances Although DFS is a widespread, worldwide technique, no books focused on this subject have been available until now. Dynamic Force Spectroscopy and Biomolecular Recognition provides the state of the art of experimental data analysis and theoretical procedures, making it a useful tool for researchers applying DFS to study biorecognition processes.
Read online Dynamic Force Spectroscopy and Biomolecular Recognition Buy Dynamic Force Spectroscopy and Biomolecular Recognition Download Dynamic Force Spectroscopy and Biomolecular Recognition for pc, mac, kindle, readers Download to iPad/iPhone/iOS, B&N nook Dynamic Force Spectroscopy and Biomolecular Recognition
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